US FDA panel says popular decongestant used in cold medicines ineffective

The panel unanimously voted against the effectiveness of orally administered phenylephrine as a nasal decongestant, adding that no more trials were required to prove otherwise. The panel vote could lead to the removal of oral phenylephrine, which is a major component of popular products like Benadryl, Advil and Tylenol, from the FDA's list of approved OTC ingredients, barring its sale in the United States.

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